Abstract
The view of intermediate filaments as static cytoskeletal elements is changing. Studies of exogenous intermediate filament proteins, either microinjected or expressed from transfected genes, have demonstrated that a continuous incorporation of subunits into the polymerized filaments is taking place. This incorporation appears to be required for maintaining normal cytoplasmic networks of intermediate filaments. At the post-translational level, phosphorylation is an important factor in regulating dynamic aspects of intermediate filament organization and structure.
| Original language | Undefined/Unknown |
|---|---|
| Pages (from-to) | 99–104 |
| Journal | Current Opinion in Cell Biology |
| Volume | 4 |
| Issue number | 1 |
| Publication status | Published - 1992 |
| MoE publication type | A2 Review article in a scientific journal |