Influence of the network modifier content on the bioactivity of silicate glasses

JP Borrajo, S Liste, J Serra, P Gonzalez, S Chiussi, B Leon, M Perez-Amor, HO Ylanen, Mikko Hupa

    Research output: Contribution to journalArticleScientificpeer-review

    23 Citations (Scopus)


    The influence of the substitution of calcium oxide for sodium oxide in the composition of silica-based glasses on the in vitro bioactivity is presented. Valuable information on the active Si-O groups present in the glasses is obtained by Fourier Transform Raman and Infrared spectroscopies. In vitro test analysis by Scanning Electron Microscopy and Energy Dispersive X-ray Analysis show a correlation between the network disruption induced by the modifier type and the bioactive process. It is demonstrated that glasses with high SiO2 content can be bioactive depending on the alkali/alkali-earth modifiers ratio included into the vitreous silica network.
    Original languageUndefined/Unknown
    Pages (from-to)23–26
    Number of pages4
    JournalKey Engineering Materials
    Issue numberBioceramics 16
    Publication statusPublished - 2004
    MoE publication typeA1 Journal article-refereed


    • bioactive glasses
    • bioactivity
    • FTIR
    • network modifiers
    • Raman

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