Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

Esa Toukoniitty; Päivi Mäki-Arvela; Narendra Kumar; Tapio Salmi; Dmitry Yu Murzin

doi:10.1016/S0920-5861(03)00004-X

Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

Esa Toukoniitty, Päivi Mäki-Arvela, Narendra Kumar, Tapio Salmi, Dmitry Yu Murzin^*

^*Corresponding author for this work

Laboratory of Industrial Chemistry and Reaction Engineering

Research output: Contribution to journal › Conference article › Scientific › peer-review

11 Citations (Scopus)

Abstract

The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.

Original language	English
Pages (from-to)	189-193
Number of pages	5
Journal	Catalysis Today
Volume	79-80
DOIs	https://doi.org/10.1016/S0920-5861(03)00004-X
Publication status	Published - 30 Apr 2003
MoE publication type	A4 Article in a conference publication
Event	Catalysis in Multiphase Reactors - Naples, Italy Duration: 29 May 2000 → 29 May 2000

Keywords

1-Phenyl-1,2-propanedione
Mass transfer
Pt catalysts

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10.1016/S0920-5861(03)00004-X

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title = "Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts",

abstract = "The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.",

keywords = "1-Phenyl-1,2-propanedione, Mass transfer, Pt catalysts",

author = "Esa Toukoniitty and P{\"a}ivi M{\"a}ki-Arvela and Narendra Kumar and Tapio Salmi and Murzin, {Dmitry Yu}",

note = "Funding Information: This work is part of the activities at the {\AA}bo Akademi Process Chemistry Group within the Finnish Centre of Excellence Programme (2000–2005) by the Academy of Finland. Financial support from Finnish Graduate School in Chemical Engineering (GSCE) is gratefully acknowledged. Copyright: Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.; Catalysis in Multiphase Reactors ; Conference date: 29-05-2000 Through 29-05-2000",

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doi = "10.1016/S0920-5861(03)00004-X",

language = "English",

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T1 - Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

AU - Toukoniitty, Esa

AU - Mäki-Arvela, Päivi

AU - Kumar, Narendra

AU - Salmi, Tapio

AU - Murzin, Dmitry Yu

N1 - Funding Information: This work is part of the activities at the Åbo Akademi Process Chemistry Group within the Finnish Centre of Excellence Programme (2000–2005) by the Academy of Finland. Financial support from Finnish Graduate School in Chemical Engineering (GSCE) is gratefully acknowledged. Copyright: Copyright 2004 Elsevier Science B.V., Amsterdam. All rights reserved.

PY - 2003/4/30

Y1 - 2003/4/30

N2 - The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.

AB - The influence of mass transfer limitations on the enantio- and regioselectivity in hydrogenation of 1-phenyl-1,2-propanedione was studied. Gas-liquid mass transfer limitation as well as liquid-solid mass transfer limitation did not influence the enantio- and regioselectivity of the reaction, compared to the performance of the system under kinetic control. Under various regimes, the enantiomeric excess of the (R)-1-hydroxy-1-phenylpropanone was about 55% and regioselectivity remained at about 10, which makes process scale-up with respect to enantio- and regioselectivity straightforward.

KW - 1-Phenyl-1,2-propanedione

KW - Mass transfer

KW - Pt catalysts

UR - http://www.scopus.com/inward/record.url?scp=0038558317&partnerID=8YFLogxK

U2 - 10.1016/S0920-5861(03)00004-X

DO - 10.1016/S0920-5861(03)00004-X

M3 - Conference article

AN - SCOPUS:0038558317

SN - 0920-5861

VL - 79-80

SP - 189

EP - 193

JO - Catalysis Today

JF - Catalysis Today

T2 - Catalysis in Multiphase Reactors

Y2 - 29 May 2000 through 29 May 2000

ER -

Influence of mass transfer on regio- and enantioselectivity in hydrogenation of 1-phenyl-1,2-propanedione over modified Pt catalysts

Abstract

Keywords

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