In vitro behavior of yttrium silica sol-​gel microspheres

D Cacaina, R Viitala, M Jokinen, H Ylanen, Mikko Hupa, S Simon

    Research output: Chapter in Book/Conference proceedingConference contributionScientificpeer-review


    Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.
    Original languageUndefined/Unknown
    Title of host publicationProceedings of the 17th International Symposium of Ceramics in Medicine, The Annual Meeting of the International Society for Ceramics in Medicine
    EditorsLi Panjian, Zhang Kai, Colwell Clifford W.
    PublisherTrans Tech Publications
    ISBN (Print)0-87849-961-X
    Publication statusPublished - 2004
    MoE publication typeA4 Article in a conference publication
    Eventconference; 2004-12-08; 2004-12-12 - New Orleans, Louisiana, US
    Duration: 8 Dec 200412 Dec 2004


    Conferenceconference; 2004-12-08; 2004-12-12

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