In situ potentiometry and ellipsometry: a promising tool to study biofouling of potentiometric sensors

Grzegorz Lisak, Thomas Arnebrant, Andrzej Lewenstam, Johan Bobacka, Tautgirdas Ruzgas

Research output: Contribution to journalArticleScientificpeer-review

33 Citations (Scopus)


In situ potentiometry and null ellipsometry was combined and used as a tool to follow the kinetics of biofouling of ion-selective electrodes (ISEs). The study was performed using custom-made solid-contact K+-ISEs consisting of a gold surface with immobilized 6-(ferrocenyl)hexanethiol as ion-to-electron transducer that was coated with a potassium-selective plasticized polymer membrane. The electrode potential and the ellipsometric signal (corresponding to the amount of adsorbed protein) were recorded simultaneously during adsorption of bovine serum albumin (BSA) at the surface of the K+-ISEs. This in situ method may become useful in developing sensors with minimized biofouling.
Original languageUndefined/Unknown
Pages (from-to)3009–3014
JournalAnalytical Chemistry
Issue number6
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed

Cite this