Highly enantio- and diastereoselective one-pot reactions in aqueous media: Combined asymmetric Rh-catalyzed conjugate addition/metal-mediated allylation

S Kallstrom, Jagt RBC, R Sillanpaa, BL Feringa, AJ Minnaard, Reko Leino

    Research output: Contribution to journalArticleScientificpeer-review

    18 Citations (Scopus)


    1,3-Disubstituted, enantiopure cyclohexanols have been prepared in very high diastereoselectivities and good yields by a concise one-pot method combining the enantioselective rhodium-catalyzed conjugate addition of arylboronic acids with indium-mediated allylation into a highly efficient one-pot reaction in aqueous media. (c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2006.
    Original languageUndefined/Unknown
    Pages (from-to)3826–3833
    Number of pages8
    JournalEuropean Journal of Organic Chemistry
    Issue number17
    Publication statusPublished - 2006
    MoE publication typeA1 Journal article-refereed


    • allylation
    • conjugate addition
    • diastereoselectivity
    • asymmetric synthesis

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