High-definition tDCS of the temporo-parietal cortex enhances access to newly learned words

G Perceval, AK Martin, DA Copland, Matti Laine, M Meinzer

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)

Abstract

Learning associations between words and their referents is crucial for language learning in thedeveloping and adult brain and for language re-learning after neurological injury. Non-invasivetranscranial direct current stimulation (tDCS) to the posterior temporo-parietal cortex has beensuggested to enhance this process. However, previous studies employed standard tDCS set-upsthat induce diffuse current flow in the brain, preventing the attribution of stimulation effects to thetarget region. This study employed high-definition tDCS (HD-tDCS) that allowed the current flow tobe constrained to the temporo-parietal cortex, to clarify its role in novel word learning. In a shamcontrolled,double-blind, between-subjects design, 50 healthy adults learned associations betweenlegal non-words and unfamiliar object pictures. Participants were stratified by baseline learning abilityon a short version of the learning paradigm and pairwise randomized to active (20 mins; N = 25) or sham(40 seconds; N = 25) HD-tDCS. Accuracy was comparable during the baseline and experimental phasesin both HD-tDCS conditions. However, active HD-tDCS resulted in faster retrieval of correct word-picturepairs. Our findings corroborate the critical role of the temporo-parietal cortex in novel wordlearning, which has implications for current theories of language acquisition.

Original languageUndefined/Unknown
Pages (from-to)
Number of pages9
JournalScientific Reports
Volume7
DOIs
Publication statusPublished - 2017
MoE publication typeA1 Journal article-refereed

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