Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis

Silvia Sabatini; Partho Sen; Fabrizia Carli; Samantha Pezzica; Chiara Rosso; Erminia Lembo; Ornella Verrastro; Ann Daly; Olivier Govaere; Simon Cockell; Tuulia Hyotylainen; Geltrude Mingrone; Elisabetta Bugianesi; Quentin M. Anstee; Matej Oresic; Amalia Gastaldelli

doi:10.1016/j.xcrm.2024.101820

Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis

Silvia Sabatini
, Partho Sen
, Fabrizia Carli
, Samantha Pezzica
, Chiara Rosso
, Erminia Lembo
, Ornella Verrastro
, Ann Daly
, Olivier Govaere
, Simon Cockell
, Tuulia Hyotylainen
, Geltrude Mingrone
, Elisabetta Bugianesi
, Quentin M. Anstee
, Matej Oresic
, Amalia Gastaldelli

Turku Bioscience Centre

Research output: Contribution to journal › Article › Scientific › peer-review

14 Citations (Scopus)

43 Downloads (Pure)

Original language	English
Article number	101820
Number of pages	14
Journal	Cell Reports Medicine
Volume	5
Issue number	11
DOIs	https://doi.org/10.1016/j.xcrm.2024.101820
Publication status	Published - 19 Nov 2024
MoE publication type	A1 Journal article-refereed

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10.1016/j.xcrm.2024.101820Licence: CC BY

PIIS2666379124005913Final published version, 3.93 MBLicence: CC BY

https://urn.fi/URN:NBN:fi-fe202501276937

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Sabatini, S., Sen, P., Carli, F., Pezzica, S., Rosso, C., Lembo, E., Verrastro, O., Daly, A., Govaere, O., Cockell, S., Hyotylainen, T., Mingrone, G., Bugianesi, E., Anstee, Q. M., Oresic, M., & Gastaldelli, A. (2024). Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis. Cell Reports Medicine, 5(11), Article 101820. https://doi.org/10.1016/j.xcrm.2024.101820

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title = "Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis",

keywords = "MASLD, liver fibrosis, insulin resistance, gluconeogenesis, hepatic glucose production, fluxomics, genome-scale metabolic modeling, type 2 diabetes, NASH, MASH",

author = "Silvia Sabatini and Partho Sen and Fabrizia Carli and Samantha Pezzica and Chiara Rosso and Erminia Lembo and Ornella Verrastro and Ann Daly and Olivier Govaere and Simon Cockell and Tuulia Hyotylainen and Geltrude Mingrone and Elisabetta Bugianesi and Anstee, \{Quentin M.\} and Matej Oresic and Amalia Gastaldelli",

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doi = "10.1016/j.xcrm.2024.101820",

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Sabatini, S, Sen, P, Carli, F, Pezzica, S, Rosso, C, Lembo, E, Verrastro, O, Daly, A, Govaere, O, Cockell, S, Hyotylainen, T, Mingrone, G, Bugianesi, E, Anstee, QM, Oresic, M & Gastaldelli, A 2024, 'Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis', Cell Reports Medicine, vol. 5, no. 11, 101820. https://doi.org/10.1016/j.xcrm.2024.101820

TY - JOUR

T1 - Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis

AU - Sabatini, Silvia

AU - Sen, Partho

AU - Carli, Fabrizia

AU - Pezzica, Samantha

AU - Rosso, Chiara

AU - Lembo, Erminia

AU - Verrastro, Ornella

AU - Daly, Ann

AU - Govaere, Olivier

AU - Cockell, Simon

AU - Hyotylainen, Tuulia

AU - Mingrone, Geltrude

AU - Bugianesi, Elisabetta

AU - Anstee, Quentin M.

AU - Oresic, Matej

AU - Gastaldelli, Amalia

PY - 2024/11/19

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KW - MASLD

KW - liver fibrosis

KW - insulin resistance

KW - gluconeogenesis

KW - hepatic glucose production

KW - fluxomics

KW - genome-scale metabolic modeling

KW - type 2 diabetes

KW - NASH

KW - MASH

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=aboakademi&SrcAuth=WosAPI&KeyUT=WOS:001361172300001&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.1016/j.xcrm.2024.101820

DO - 10.1016/j.xcrm.2024.101820

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JO - Cell Reports Medicine

JF - Cell Reports Medicine

IS - 11

M1 - 101820

ER -

Hepatic glucose production rises with the histological severity of metabolic dysfunction-associated steatohepatitis

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