Global SUMOylation on active chromatin is an acute heat stress response restricting transcription

EA Niskanen, M Malinen, P Sutinen, S Toropainen, V Paakinaho, Johanna Vihervaara, Jenny Joutsen, MU Kaikkonen, Lea Sistonen, JJ Palvimo

Research output: Contribution to journalArticleScientificpeer-review

43 Citations (Scopus)

Abstract

Conclusions: HS-triggered SUMOylation targets promoters and enhancers of actively transcribed genes where it restricts the transcriptional activity of the HS-induced genes. PIAS1-mediated promoter SUMOylation is likely to regulate Pol2-associated factors in HS.
Original languageUndefined/Unknown
Pages (from-to)1–19
Number of pages19
JournalGENOME BIOLOGY
Volume16
DOIs
Publication statusPublished - 2015
MoE publication typeA1 Journal article-refereed

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