Abstract
Hybrid macromolecular antioxidants has evolved into a mature research field last three decades. The main concept of this area was to design polymer conjugates that combine in one structure the hydrophilic properties of a polymer backbone and biological efficiency of hydrophobic antioxidants. Over the years, the understanding of different aspects of such approach has grown. In general, meticulous selection of each component is essential to obtain the conjugate with required properties. This review overview a plethora of hybrid macromolecular antioxidants synthesized over the last 20 years, together with the discussion their physicochemical properties and application for biomedical purposes.
| Original language | English |
|---|---|
| Pages (from-to) | 2655-2668 |
| Number of pages | 14 |
| Journal | Polymers for Advanced Technologies |
| Volume | 32 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2021 |
| MoE publication type | A2 Review article in a scientific journal |
Funding
The authors thank all Master and PhD students, employees, and faculty staff of Saint‐Petersburg State University, Department of Chemistry, Chair of Polymer Chemistry for their help and support. Sergey Filippov acknowledges the financial support of the grant BR05236446 from the Ministry of Science (Republic of Kazakhstan).
Keywords
- amphiphilic polymers
- hybrid macromolecular antioxidants
- mechanism of antioxidant activity
- sterically hindered phenols
- structure