Future and the past of polymeric antioxidants

Sergey K. Filippov*, Nina Domnina, Violetta Vol'eva

*Corresponding author for this work

Research output: Contribution to journalReview Article or Literature Reviewpeer-review

7 Citations (Scopus)


Hybrid macromolecular antioxidants has evolved into a mature research field last three decades. The main concept of this area was to design polymer conjugates that combine in one structure the hydrophilic properties of a polymer backbone and biological efficiency of hydrophobic antioxidants. Over the years, the understanding of different aspects of such approach has grown. In general, meticulous selection of each component is essential to obtain the conjugate with required properties. This review overview a plethora of hybrid macromolecular antioxidants synthesized over the last 20 years, together with the discussion their physicochemical properties and application for biomedical purposes.

Original languageEnglish
Pages (from-to)2655-2668
Number of pages14
JournalPolymers for Advanced Technologies
Issue number7
Publication statusPublished - Jul 2021
MoE publication typeA2 Review article in a scientific journal


  • amphiphilic polymers
  • hybrid macromolecular antioxidants
  • mechanism of antioxidant activity
  • sterically hindered phenols
  • structure


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