Florol synthesis via Prins cyclization over hierarchical beta zeolites

Nataliya Shcherban*, Roman Barakov, Basile Lasne, Päivi Mäki-Arvela, Mariya Shamzhy, Igor Bezverkhyy, Johan Wärnå, Dmitry Yu Murzin

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)
32 Downloads (Pure)

Abstract

A set of hierarchical beta zeolites with variable Si/Al ratios, nanoparticle sizes, textural and acidic properties was prepared using a hydrothermal treatment of a concentrated alkali metal-free protic acid-containing zeolite gel-precursor. The obtained catalysts were investigated in the Prins cyclization of isovaleraldehyde with isoprenol yielding a commercially valuable tetrahydropyranol (Florol). The highest yield of the desired product (55.4%) was achieved over a zeolite catalyst possessing moderate acidity, developed mesoporosity (Vmeso 0.60 cm3/g) and a high external surface area (290 m2/g). Preferable formation of substituted tetrahydropyranol over weak- and medium-strength Brønsted acid sites, on the one hand, and generation of the undesired dehydration products mainly over strong Brønsted acid sites, on the other hand, occurring in parallel routes were supported by the kinetic analysis of the reaction network.

Original languageEnglish
Article number112683
Number of pages13
JournalMolecular Catalysis
Volume531
DOIs
Publication statusPublished - Oct 2022
MoE publication typeA1 Journal article-refereed

Keywords

  • Florol, Acid sites
  • Hierarchical zeolite
  • Prins cyclisation
  • Tetrahydropyranol

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