F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease

J Rokka; A Snellman; M Kaasalainen; J Salonen; C Zona; La Ferla B; F Nicotra; Re F; M Masserini; S Forsback; F Lopez-Picon; JO Rinne; M Haaparanta-Solin; Olof Solin

doi:10.1016/j.ejps.2016.03.016

F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease

J Rokka
, A Snellman
, M Kaasalainen
, J Salonen
, C Zona
, La Ferla B
, F Nicotra
, Re F
, M Masserini
, S Forsback
, F Lopez-Picon
, JO Rinne
, M Haaparanta-Solin
, Olof Solin

Turku PET Centre

Research output: Contribution to journal › Article › Scientific › peer-review

9 Citations (Scopus)

Abstract

Although the studied functionalized F-18-NLs were not suitable for PET imaging as such, the synthesis techniques introduced in this study can be utilized to modify the biological behavior of F-18-labeled NLs. (C) 2016 Elsevier B.V. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	257–266
Number of pages	10
Journal	European Journal of Pharmaceutical Sciences
Volume	88
DOIs	https://doi.org/10.1016/j.ejps.2016.03.016
Publication status	Published - 2016
MoE publication type	A1 Journal article-refereed

Keywords

Alzheimer's disease
beta-amyloid plaques
Functionalized nanoliposomes
Nucleophilic 18F-fluorination
Positron emission tomography (PET)

Access to Document

10.1016/j.ejps.2016.03.016

Cite this

Rokka, J., Snellman, A., Kaasalainen, M., Salonen, J., Zona, C., Ferla B, L., Nicotra, F., F, R., Masserini, M., Forsback, S., Lopez-Picon, F., Rinne, JO., Haaparanta-Solin, M., & Solin, O. (2016). F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease. European Journal of Pharmaceutical Sciences, 88, 257–266. https://doi.org/10.1016/j.ejps.2016.03.016

@article{d99c611942d34848bc5d35d5a24c3600,

title = "F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease",

abstract = "Although the studied functionalized F-18-NLs were not suitable for PET imaging as such, the synthesis techniques introduced in this study can be utilized to modify the biological behavior of F-18-labeled NLs. (C) 2016 Elsevier B.V. All rights reserved.",

keywords = "Alzheimer's disease, beta-amyloid plaques, Functionalized nanoliposomes, Nucleophilic 18F-fluorination, Positron emission tomography (PET), Alzheimer's disease, beta-amyloid plaques, Functionalized nanoliposomes, Nucleophilic 18F-fluorination, Positron emission tomography (PET), Alzheimer's disease, beta-amyloid plaques, Functionalized nanoliposomes, Nucleophilic 18F-fluorination, Positron emission tomography (PET)",

author = "J Rokka and A Snellman and M Kaasalainen and J Salonen and C Zona and \{Ferla B\}, La and F Nicotra and Re F and M Masserini and S Forsback and F Lopez-Picon and JO Rinne and M Haaparanta-Solin and Olof Solin",

year = "2016",

doi = "10.1016/j.ejps.2016.03.016",

language = "Odefinierat/ok{\"a}nt",

volume = "88",

pages = "257{\textendash}266",

journal = "European Journal of Pharmaceutical Sciences",

issn = "0928-0987",

publisher = "Elsevier",

}

Rokka, J, Snellman, A, Kaasalainen, M, Salonen, J, Zona, C, Ferla B, L, Nicotra, F, F, R, Masserini, M, Forsback, S, Lopez-Picon, F, Rinne, JO, Haaparanta-Solin, M & Solin, O 2016, 'F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease', European Journal of Pharmaceutical Sciences, vol. 88, pp. 257–266. https://doi.org/10.1016/j.ejps.2016.03.016

TY - JOUR

T1 - F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease

AU - Rokka, J

AU - Snellman, A

AU - Kaasalainen, M

AU - Salonen, J

AU - Zona, C

AU - Ferla B, La

AU - Nicotra, F

AU - F, Re

AU - Masserini, M

AU - Forsback, S

AU - Lopez-Picon, F

AU - Rinne, JO

AU - Haaparanta-Solin, M

AU - Solin, Olof

PY - 2016

Y1 - 2016

N2 - Although the studied functionalized F-18-NLs were not suitable for PET imaging as such, the synthesis techniques introduced in this study can be utilized to modify the biological behavior of F-18-labeled NLs. (C) 2016 Elsevier B.V. All rights reserved.

AB - Although the studied functionalized F-18-NLs were not suitable for PET imaging as such, the synthesis techniques introduced in this study can be utilized to modify the biological behavior of F-18-labeled NLs. (C) 2016 Elsevier B.V. All rights reserved.

KW - Alzheimer's disease

KW - beta-amyloid plaques

KW - Functionalized nanoliposomes

KW - Nucleophilic 18F-fluorination

KW - Positron emission tomography (PET)

KW - Alzheimer's disease

KW - beta-amyloid plaques

KW - Functionalized nanoliposomes

KW - Nucleophilic 18F-fluorination

KW - Positron emission tomography (PET)

KW - Alzheimer's disease

KW - beta-amyloid plaques

KW - Functionalized nanoliposomes

KW - Nucleophilic 18F-fluorination

KW - Positron emission tomography (PET)

U2 - 10.1016/j.ejps.2016.03.016

DO - 10.1016/j.ejps.2016.03.016

M3 - Artikel

SN - 0928-0987

VL - 88

SP - 257

EP - 266

JO - European Journal of Pharmaceutical Sciences

JF - European Journal of Pharmaceutical Sciences

ER -