F-18-labeling syntheses and preclinical evaluation of functionalized nanoliposomes for Alzheimer's disease

J Rokka, A Snellman, M Kaasalainen, J Salonen, C Zona, La Ferla B, F Nicotra, Re F, M Masserini, S Forsback, F Lopez-Picon, JO Rinne, M Haaparanta-Solin, Olof Solin

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4 Citations (Scopus)

Abstract

Although the studied functionalized F-18-NLs were not suitable for PET imaging as such, the synthesis techniques introduced in this study can be utilized to modify the biological behavior of F-18-labeled NLs. (C) 2016 Elsevier B.V. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)257–266
Number of pages10
JournalEuropean Journal of Pharmaceutical Sciences
Volume88
DOIs
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed

Keywords

  • Alzheimer's disease
  • beta-amyloid plaques
  • Functionalized nanoliposomes
  • Nucleophilic 18F-fluorination
  • Positron emission tomography (PET)

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