Enabling [18F]-bicyclo[6.1.0]nonyne for oligonucleotide conjugation for positron emission tomography applications: [18F]-anti-microRNA-21 as an example

Xiang-Guo Li; Anne Roivainen; Jörgen Bergman; Arttu Heinonen; Frank Bengel; Thomas Thum; Juhani Knuuti

doi:10.1039/C5CC02618K

Enabling [18F]-bicyclo[6.1.0]nonyne for oligonucleotide conjugation for positron emission tomography applications: [18F]-anti-microRNA-21 as an example

Xiang-Guo Li
, Anne Roivainen
, Jörgen Bergman
, Arttu Heinonen
, Frank Bengel
, Thomas Thum
, Juhani Knuuti

Turku PET Centre

Research output: Contribution to journal › Article › Scientific › peer-review

15 Citations (Scopus)

Abstract

A bicyclononyne-based prosthetic group has been developed for F-18-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.

Original language	Undefined/Unknown
Pages (from-to)	9821–9824
Journal	Chemical Communications
Volume	51
Issue number	48
DOIs	https://doi.org/10.1039/C5CC02618K
Publication status	Published - 2015
MoE publication type	A1 Journal article-refereed

Access to Document

10.1039/C5CC02618K

http://pubs.rsc.org/en/Content/ArticleLanding/2015/CC/C5CC02618K

Cite this

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title = "Enabling [18F]-bicyclo[6.1.0]nonyne for oligonucleotide conjugation for positron emission tomography applications: [18F]-anti-microRNA-21 as an example",

abstract = "A bicyclononyne-based prosthetic group has been developed for F-18-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.",

author = "Xiang-Guo Li and Anne Roivainen and J{\"o}rgen Bergman and Arttu Heinonen and Frank Bengel and Thomas Thum and Juhani Knuuti",

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T1 - Enabling [18F]-bicyclo[6.1.0]nonyne for oligonucleotide conjugation for positron emission tomography applications: [18F]-anti-microRNA-21 as an example

AU - Li, Xiang-Guo

AU - Roivainen, Anne

AU - Bergman, Jörgen

AU - Heinonen, Arttu

AU - Bengel, Frank

AU - Thum, Thomas

AU - Knuuti, Juhani

N1 - PET.

PY - 2015

Y1 - 2015

N2 - A bicyclononyne-based prosthetic group has been developed for F-18-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.

AB - A bicyclononyne-based prosthetic group has been developed for F-18-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.

U2 - 10.1039/C5CC02618K

DO - 10.1039/C5CC02618K

M3 - Artikel

SN - 1359-7345

VL - 51

SP - 9821

EP - 9824

JO - Chemical Communications

JF - Chemical Communications

IS - 48

ER -