Electrochemical Investigation of Self-Assembling Monolayers toward Ultrasensitive Sensing

Angelo Tricase*, Anna Imbriano, Eleonora Macchia, Rosaria Anna Picca, Davide Blasi, Luisa Torsi, Paolo Bollella

*Corresponding author for this work

Research output: Chapter in Book/Conference proceedingConference contributionScientificpeer-review

2 Citations (Scopus)

Abstract

In this paper we report a combined theoretical and experimental approach for analyzing Self Assembled Monolayers (SAMs) modified electrodes. Three different SAMs were compared, consisting in a mixed SAMs of amides and carboxylic groups (Deactivated SAMs), a SAM functionalized with an antibody (Anti-IgG SAMs), and SAM functionalized with two different proteins, Anti-IgG and Bovine Serum Albumin (BSA). Each of these samples is used to describe a different component of a SAMs modified gold electrode implemented in an Electrolyte Gated - Organic Field Effect Transistor Biosensor, where the presence of a diffuse hydrogen bonding between SAMs chains plays a key role for reaching the performance of this device, able to reach the single molecule limit of detection.

Original languageEnglish
Title of host publication2022 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS)
Publisherthe Institute of Electrical and Electronics Engineers, Inc.
ISBN (Electronic)9781665442732
ISBN (Print)9781665483605
DOIs
Publication statusPublished - 2022
MoE publication typeA4 Article in a conference publication
Event2022 IEEE International Conference on Flexible and Printable Sensors and Systems, FLEPS 2022 - Vienna, Austria
Duration: 10 Jul 202213 Jul 2022

Conference

Conference2022 IEEE International Conference on Flexible and Printable Sensors and Systems, FLEPS 2022
Country/TerritoryAustria
CityVienna
Period10/07/2213/07/22

Keywords

  • anti-IgG
  • cyclic voltammetry
  • hydrogen bonding
  • modified electrodes
  • self assembled monolayers

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