Three different modifiers, (-)-cinchonidine, 10,11-dihydrocinchonidine and (+)-cinchonine were investigated in the enantioselective hydrogenation of an unsymmetrical dione, 1-phenyl-1,2-propanedione, over a commercial Pt/Al(2)O(3) catalyst. The catalytic activity, as well as the regio- and enantioselectivity in the hydroxyketones and diols formed were compared.
|Number of pages||10|
|Journal||Reaction Kinetics and Catalysis Letters|
|Publication status||Published - 2002|
|MoE publication type||A1 Journal article-refereed|
- chiral modifier
- enantioselective hydrogenation