Effect of modifier structure in the enantioselective hydrogenation of 1-phenyl-1,2-propanedione

E Toukoniitty, Päivi Mäki-Arvela, R Sjoholm, Reko Leino, T Salmi, Dmitry Murzin

Research output: Contribution to journalArticleScientificpeer-review

15 Citations (Scopus)

Abstract

Three different modifiers, (-)-cinchonidine, 10,11-dihydrocinchonidine and (+)-cinchonine were investigated in the enantioselective hydrogenation of an unsymmetrical dione, 1-phenyl-1,2-propanedione, over a commercial Pt/Al(2)O(3) catalyst. The catalytic activity, as well as the regio- and enantioselectivity in the hydroxyketones and diols formed were compared.
Original languageUndefined/Unknown
Pages (from-to)21–30
Number of pages10
JournalReaction Kinetics and Catalysis Letters
Volume75
Issue number1
Publication statusPublished - 2002
MoE publication typeA1 Journal article-refereed

Keywords

  • chiral modifier
  • dione
  • enantioselective hydrogenation

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