Dual functional construct containing kartogenin releasing microtissues and curcumin for cartilage regeneration

Negin Asgari, Fatemeh Bagheri, Mohamadreza Baghaban Eslaminejad, Mohammad Hossein Ghanian, Forogh Azam Sayahpour, Amir Mohammad Ghafari

Research output: Contribution to journalArticleScientificpeer-review

3 Citations (Scopus)
2 Downloads (Pure)

Abstract

Regeneration of articular cartilage poses a tremendous challenge due to its limited self-repair capability and inflammation at the damaged site. To generate the desired structures that mimic the structure of native tissue, microtissues with repeated functional units such as cell aggregates have been developed. Multicellular aggregates of mesenchymal stem cells (MSCs) can be used as microscale building blocks of cartilage due to their potential for cell-cell contact, cell proliferation, and differentiation.
Original languageEnglish
Article number289
JournalStem Cell Research & Therapy
Volume11
Issue number1
DOIs
Publication statusPublished - 16 Jul 2020
MoE publication typeA1 Journal article-refereed

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