Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular steatosis

Hanna Heikela, Laura Mairinoja, Suvi T. Ruohonen, Kalle T. Rytkonen, Simone de Brot, Asta Laiho, Satu Koskinen, Tomi Suomi, Laura L. Elo, Leena Strauss, Matti Poutanen*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

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Original languageEnglish
Article numbere70034
Number of pages16
JournalFASEB Journal
Volume38
Issue number17
DOIs
Publication statusPublished - Sept 2024
MoE publication typeA1 Journal article-refereed

Keywords

  • 17-hydroxysteroid dehydrogenases
  • Computer assisted image analysis
  • Lipid droplets
  • Liver steatosis
  • Nonalcoholic fatty liver disease

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