Dicarbonylchloro(pentabenzylcyclopentadienyl)ruthenium as Racemization Catalyst in the Dynamic Kinetic Resolution of Secondary Alcohols

D Mavrynsky, M Paivio, K Lundell, R Sillanpaa, LT Kanerva, Reko Leino

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    29 Citations (Scopus)

    Abstract

    Dicarbonylchloro(pentabenzylcyclopentadienyl)ruthenium has been prepared and its structure confirmed by X-ray analysis, This complex shows excellent catalytic activity and modest stability against air in racemization reactions of secondary alcohols. In Candida antarctica lipase B (CAL-B) catalyzed dynamic kinetic resolution (DKR) of 1-phenyl- and 1-(furan-2-yl)ethanol compounds, the new complex shows improved performance as an alcohol racemization catalyst in comparison with its well-known pentaphenylcyclopentadienyl analogue, hitherto considered as the leading catalyst candidate. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
    Original languageUndefined/Unknown
    Pages (from-to)1317–1320
    Number of pages4
    JournalEuropean Journal of Organic Chemistry
    Volume2009
    Issue number9
    DOIs
    Publication statusPublished - 2009
    MoE publication typeA1 Journal article-refereed

    Keywords

    • Cyclopentadienyl ligands
    • Dynamic kinetic resolution
    • Enzyme catalysis
    • Racemization
    • Ruthenium

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