Cytotoxic activity of some glycoconjugates including saponins and anthracyclines

Filip S. Ekholm, Ágnes Berényi, Lucas Lagerquist, Tiina Saloranta-Simell, István Zupkó, Gyula Schneider, János Wölfling, Reko Leino

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Many different glycoconjugates, including saponins (e.g., hellebrin) and anthracyclines (e.g., doxorubicin), are known to display cytotoxic activities. In recent work, we have developed synthetic protocols for the synthesis of various glycoconjugates, focusing on glycosylation methods for different classes of biomolecules. Simultaneously a number of saponins and anthracyclines have been generated. In this note, the cytotoxic activities of these synthesized compounds are briefly addressed. (C) 2012 Elsevier Ltd. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)295–298
Number of pages4
JournalCarbohydrate Research
Volume356
DOIs
Publication statusPublished - 2012
MoE publication typeA1 Journal article-refereed

Keywords

  • Cytotoxic activity
  • Saponins

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