Abstract
Maintenance of cellular homeostasis depends upon several pathways that allow a cell to respond and adapt to both environmental stress and changes in metabolic status. New work in this issue of The EMBO Journal reveals a mechanism of cross talk between heat shock factor 1 (HSF1), the primary regulator of the proteotoxic stress response, and AMP-activated protein kinase (AMPK), the primary sensor in the metabolic stress response.
| Original language | English |
|---|---|
| Pages (from-to) | 267-9 |
| Number of pages | 3 |
| Journal | EMBO Journal |
| Volume | 34 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 3 Feb 2015 |
| MoE publication type | A1 Journal article-refereed |
Keywords
- AMP-Activated Protein Kinases/metabolism
- Animals
- DNA-Binding Proteins/metabolism
- Heat Shock Transcription Factors
- Neoplasm Proteins/metabolism
- Neoplasms, Experimental/metabolism
- Stress, Physiological
- Transcription Factors/metabolism