BODIL: a molecular modeling environment for structure-function analysis and drug design

Jukka Lehtonen, Dan-Johan Still, Ville-V Rantanen, Jan Ekholm, Dag Björklund, Zuhair Iftikhar, Mikko Huhtala, Susanna Repo, Antti Jussila, Jussi Jaakkola, Olli Pentikäinen, Tommi Nyrönen, Tiina Salminen, Mats Gyllenberg, Mark S Johnson

Research output: Contribution to journalArticleScientificpeer-review

175 Citations (Scopus)

Abstract

BODIL is a molecular modeling environment geared to help the user to quickly identify key features of proteins critical to molecular recognition, especially (1) in drug discovery applications, and (2) to understand the structural basis for function. The program incorporates state-of-the-art graphics, sequence and structural alignment methods, among other capabilities needed in modern structure-function-drug target research. BODIL has a flexible design that allows on-the-fly incorporation of new modules, has intelligent memory management, and fast multi-view graphics. A beta version of BODIL and an accompanying tutorial are available at http://www.abo.fi/fak/mnf/bkf/research/johnson/bodil.html.
Original languageUndefined/Unknown
Pages (from-to)401–419
JournalJournal of Computer-Aided Molecular Design
Volume18
Issue number6
DOIs
Publication statusPublished - 2004
MoE publication typeA1 Journal article-refereed

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