Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro

O Lepparanta; M Vaahtio; T Peltola; D Zhang; Leena Hupa; Mikko Hupa; H Ylanen; JI Salonen; MK Viljanen; E Eerola

doi:10.1007/s10856-007-3018-5

Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro

O Lepparanta, M Vaahtio, T Peltola, D Zhang, Leena Hupa, Mikko Hupa, H Ylanen, JI Salonen, MK Viljanen, E Eerola

Research output: Contribution to journal › Article › Scientific › peer-review

197 Citations (Scopus)

Abstract

Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13-93) and a sol-gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition, although the concentration and time needed for the effect varied depending on the BAG. Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13-93 and sol-gel derived material CaPSiO II showed moderate antibacterial properties.

Original language	Undefined/Unknown
Pages (from-to)	547–551
Number of pages	5
Journal	Journal of Materials Science: Materials in Medicine
Volume	19
Issue number	2
DOIs	https://doi.org/10.1007/s10856-007-3018-5
Publication status	Published - 2008
MoE publication type	A1 Journal article-refereed

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10.1007/s10856-007-3018-5

Cite this

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title = "Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro",

abstract = "Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13-93) and a sol-gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition, although the concentration and time needed for the effect varied depending on the BAG. Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13-93 and sol-gel derived material CaPSiO II showed moderate antibacterial properties.",

author = "O Lepparanta and M Vaahtio and T Peltola and D Zhang and Leena Hupa and Mikko Hupa and H Ylanen and JI Salonen and MK Viljanen and E Eerola",

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T1 - Antibacterial effect of bioactive glasses on clinically important anaerobic bacteria in vitro

AU - Lepparanta, O

AU - Vaahtio, M

AU - Peltola, T

AU - Zhang, D

AU - Hupa, Leena

AU - Hupa, Mikko

AU - Ylanen, H

AU - Salonen, JI

AU - Viljanen, MK

AU - Eerola, E

PY - 2008

Y1 - 2008

N2 - Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13-93) and a sol-gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition, although the concentration and time needed for the effect varied depending on the BAG. Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13-93 and sol-gel derived material CaPSiO II showed moderate antibacterial properties.

AB - Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13-93) and a sol-gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition, although the concentration and time needed for the effect varied depending on the BAG. Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13-93 and sol-gel derived material CaPSiO II showed moderate antibacterial properties.

U2 - 10.1007/s10856-007-3018-5

DO - 10.1007/s10856-007-3018-5

M3 - Artikel

SN - 0957-4530

VL - 19

SP - 547

EP - 551

JO - Journal of Materials Science: Materials in Medicine

JF - Journal of Materials Science: Materials in Medicine

IS - 2

ER -