An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit <i>KRAS</i> Mutant Cancer Cell Growth

Pelin Kaya; Elisabeth Schaffner-Reckinger; Ganesh babu Manoharan; Vladimir Vukic; Alexandros Kiriazis; Mirko Ledda; Maria Burgos Renedo; Karolina Pavic; Anthoula Gaigneaux; Enrico Glaab; Daniel Kwaku Abankwa

doi:10.1021/acs.jmedchem.3c02129

An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit <i>KRAS</i> Mutant Cancer Cell Growth

Pelin Kaya
, Elisabeth Schaffner-Reckinger
, Ganesh babu Manoharan
, Vladimir Vukic
, Alexandros Kiriazis
, Mirko Ledda
, Maria Burgos Renedo
, Karolina Pavic
, Anthoula Gaigneaux
, Enrico Glaab
, Daniel Kwaku Abankwa

Turku Bioscience Centre

Research output: Contribution to journal › Article › Scientific › peer-review

11 Citations (Scopus)

47 Downloads (Pure)

Original language	English
Pages (from-to)	8569-8584
Number of pages	16
Journal	Journal of Medicinal Chemistry
Volume	67
Issue number	11
DOIs	https://doi.org/10.1021/acs.jmedchem.3c02129
Publication status	Published - 17 May 2024
MoE publication type	A1 Journal article-refereed

Access to Document

10.1021/acs.jmedchem.3c02129Licence: CC BY

kaya-et-al-2024-an-improved-pde6d-inhibitor-combines-with-sildenafil-to-inhibit-kras-mutant-cancer-cell-growthFinal published version, 5.5 MBLicence: CC BY

https://urn.fi/URN:NBN:fi-fe2025020710463

Cite this

@article{9c06b4a3248b43feada2246443be1f93,

title = "An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth",

keywords = "Assays, Toxicological synergy, Inhibitors, Cells, Bioluminescence",

author = "Pelin Kaya and Elisabeth Schaffner-Reckinger and Manoharan, \{Ganesh babu\} and Vladimir Vukic and Alexandros Kiriazis and Mirko Ledda and \{Burgos Renedo\}, Maria and Karolina Pavic and Anthoula Gaigneaux and Enrico Glaab and Abankwa, \{Daniel Kwaku\}",

year = "2024",

month = may,

day = "17",

doi = "10.1021/acs.jmedchem.3c02129",

language = "English",

volume = "67",

pages = "8569--8584",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

number = "11",

}

TY - JOUR

T1 - An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit KRAS Mutant Cancer Cell Growth

AU - Kaya, Pelin

AU - Schaffner-Reckinger, Elisabeth

AU - Manoharan, Ganesh babu

AU - Vukic, Vladimir

AU - Kiriazis, Alexandros

AU - Ledda, Mirko

AU - Burgos Renedo, Maria

AU - Pavic, Karolina

AU - Gaigneaux, Anthoula

AU - Glaab, Enrico

AU - Abankwa, Daniel Kwaku

PY - 2024/5/17

Y1 - 2024/5/17

KW - Assays

KW - Toxicological synergy

KW - Inhibitors

KW - Cells

KW - Bioluminescence

UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=aboakademi&SrcAuth=WosAPI&KeyUT=WOS:001227329700001&DestLinkType=FullRecord&DestApp=WOS_CPL

U2 - 10.1021/acs.jmedchem.3c02129

DO - 10.1021/acs.jmedchem.3c02129

M3 - Article

C2 - 38758695

SN - 0022-2623

VL - 67

SP - 8569

EP - 8584

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 11

ER -

An Improved PDE6D Inhibitor Combines with Sildenafil To Inhibit <i>KRAS</i> Mutant Cancer Cell Growth

Access to Document

Other files and links

Cite this