An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

T Blom, N Bergelin, Annika Meinander, C Löf, J.Peter Slotte, John Eriksson, Kid Törnquist

Research output: Contribution to journalArticleScientificpeer-review

33 Citations (Scopus)


Conclusions: We propose a self-amplifying loop of autocrine S1P with capacity to enhance cell survival. The mechanism provides increased understanding of the multifaceted roles of S1P in regulating cell fate during normal development and carcinogenesis.
Original languageUndefined/Unknown
Pages (from-to)1–11
Number of pages11
JournalBMC Cell Biology
Publication statusPublished - 2010
MoE publication typeA1 Journal article-refereed

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