An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

T Blom; N Bergelin; Annika Meinander; C Löf; J.Peter Slotte; John Eriksson; Kid Törnquist

doi:10.1186/1471-2121-11-45

An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

T Blom, N Bergelin, Annika Meinander, C Löf, J.Peter Slotte, John Eriksson, Kid Törnquist

Biochemistry and Cell Biology

Research output: Contribution to journal › Article › Scientific › peer-review

34 Citations (Scopus)

Abstract

Conclusions: We propose a self-amplifying loop of autocrine S1P with capacity to enhance cell survival. The mechanism provides increased understanding of the multifaceted roles of S1P in regulating cell fate during normal development and carcinogenesis.

Original language	Undefined/Unknown
Pages (from-to)	1–11
Number of pages	11
Journal	BMC Cell Biology
Volume	11
DOIs	https://doi.org/10.1186/1471-2121-11-45
Publication status	Published - 2010
MoE publication type	A1 Journal article-refereed

Access to Document

10.1186/1471-2121-11-45

Cite this

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title = "An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival",

abstract = "Conclusions: We propose a self-amplifying loop of autocrine S1P with capacity to enhance cell survival. The mechanism provides increased understanding of the multifaceted roles of S1P in regulating cell fate during normal development and carcinogenesis.",

author = "T Blom and N Bergelin and Annika Meinander and C L{\"o}f and J.Peter Slotte and John Eriksson and Kid T{\"o}rnquist",

year = "2010",

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T1 - An autocrine sphingosine-1-phosphate signaling loop enhances NF-κB-activation and survival

AU - Blom, T

AU - Bergelin, N

AU - Meinander, Annika

AU - Löf, C

AU - Slotte, J.Peter

AU - Eriksson, John

AU - Törnquist, Kid

PY - 2010

Y1 - 2010

N2 - Conclusions: We propose a self-amplifying loop of autocrine S1P with capacity to enhance cell survival. The mechanism provides increased understanding of the multifaceted roles of S1P in regulating cell fate during normal development and carcinogenesis.

AB - Conclusions: We propose a self-amplifying loop of autocrine S1P with capacity to enhance cell survival. The mechanism provides increased understanding of the multifaceted roles of S1P in regulating cell fate during normal development and carcinogenesis.

U2 - 10.1186/1471-2121-11-45

DO - 10.1186/1471-2121-11-45

M3 - Artikel

SN - 1471-2121

VL - 11

SP - 1

EP - 11

JO - BMC Cell Biology

JF - BMC Cell Biology

ER -