An approach to chemoenzymatic DKR of amines in Soxhlet apparatus

Denys Mavrynsky, Reko Leino

    Research output: Contribution to journalArticleScientificpeer-review

    8 Citations (Scopus)

    Abstract

    The coexistence of thermolabile enzyme and metal catalyst for racemization of amines in chemoenzymatic dynamic kinetic resolution, requiring high temperature of operation, is enabled by carrying out the reaction in modified Soxhlet extraction system. Initial insights into the scope and limitations of the developed reaction system are discussed. (C) 2013 Elsevier B. V. All rights reserved.
    Original languageUndefined/Unknown
    Pages (from-to)161–166
    Number of pages6
    JournalJournal of Organometallic Chemistry
    Volume760
    DOIs
    Publication statusPublished - 2014
    MoE publication typeA1 Journal article-refereed

    Keywords

    • Chemoenzymatic synthesis
    • Chiral amines
    • DKR
    • Shvo's catalyst
    • Soxhlet extraction

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