A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity

Reijo Lahti; Katariina Pohjanoksa; Taru Pitkäranta; Pirkko Heikinheimo; Tiina Salminen; Peter Meyer; Jukka Heinonen

doi:10.1021/bi00476a017

A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity

Reijo Lahti
, Katariina Pohjanoksa
, Taru Pitkäranta
, Pirkko Heikinheimo
, Tiina Salminen
, Peter Meyer
, Jukka Heinonen

Research output: Contribution to journal › Article › Scientific › peer-review

45 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	5761–5766
Number of pages	6
Journal	Biochemistry
Volume	29
DOIs	https://doi.org/10.1021/bi00476a017
Publication status	Published - 1990
MoE publication type	A1 Journal article-refereed

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10.1021/bi00476a017

Cite this

Lahti, R., Pohjanoksa, K., Pitkäranta, T., Heikinheimo, P., Salminen, T., Meyer, P., & Heinonen, J. (1990). A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity. Biochemistry, 29, 5761–5766. https://doi.org/10.1021/bi00476a017

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author = "Reijo Lahti and Katariina Pohjanoksa and Taru Pitk{\"a}ranta and Pirkko Heikinheimo and Tiina Salminen and Peter Meyer and Jukka Heinonen",

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doi = "10.1021/bi00476a017",

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Lahti, R, Pohjanoksa, K, Pitkäranta, T, Heikinheimo, P, Salminen, T, Meyer, P & Heinonen, J 1990, 'A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity', Biochemistry, vol. 29, pp. 5761–5766. https://doi.org/10.1021/bi00476a017

A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity. / Lahti, Reijo; Pohjanoksa, Katariina; Pitkäranta, Taru et al.
In: Biochemistry, Vol. 29, 1990, p. 5761–5766.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity

AU - Lahti, Reijo

AU - Pohjanoksa, Katariina

AU - Pitkäranta, Taru

AU - Heikinheimo, Pirkko

AU - Salminen, Tiina

AU - Meyer, Peter

AU - Heinonen, Jukka

PY - 1990

Y1 - 1990

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DO - 10.1021/bi00476a017

M3 - Artikel

SN - 0006-2960

VL - 29

SP - 5761

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JO - Biochemistry

JF - Biochemistry

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