A MILP-method for optimizing a preparative simulated moving bed chromatographic separation process

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Abstract

In the present paper a mixed integer linear programming (MILP) formulation for a chromatographic separation process is described. What in this case makes the paper especially interesting, is the fact that hardly any mathematical programming method has been described for this kind of separation system, although many formulations have been described for other kinds of separation systems, e.g. distillation. The objective is to formulate the process in a linear form and to optimize the production.

Original languageEnglish
Pages (from-to)S487-S490
JournalComputers and Chemical Engineering
Volume23
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 1 Jun 1999
MoE publication typeA1 Journal article-refereed

Keywords

  • Chromatographic separation
  • Mixed integer linear programming
  • Optimization
  • Production planning
  • Simulated moving bed

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