A label-free immunosensor based on a graphene water-gated field-effect transistor

Rosaria Anna Picca, Davide Blasi, Eleonora MacChia, Kyriaki Manoli, Cinzia Di Franco, Gaetano Scamarcio, Fabrizio Torricelli, Amaia Zurutuza, Ilargi Napal, Alba Centeno, Luisa Torsi

    Research output: Chapter in Book/Conference proceedingConference contributionScientificpeer-review

    4 Citations (Scopus)

    Abstract

    Electrolyte-gated graphene field-effect transistors are here proposed for biosensing applications. To this end, a label-free immunosensor based on this technology is employed for the sensitive and selective detection of IgG. Differently from the typical approach based on the bioreceptor immobilization onto a graphene layer, in this work sensitivity in the lower femtomolar range can be reached thanks to the formation of a closely packed layer of anti-IgG receptors anchored to the gold gate electrode.

    Original languageEnglish
    Title of host publicationProceedings - 2019 8th International Workshop on Advances in Sensors and Interfaces, IWASI 2019
    Publisherthe Institute of Electrical and Electronics Engineers, Inc.
    Pages136-138
    Number of pages3
    ISBN (Electronic)9781728105567
    DOIs
    Publication statusPublished - Jun 2019
    MoE publication typeA4 Article in a conference publication
    Event8th International Workshop on Advances in Sensors and Interfaces, IWASI 2019 - Otranto, Italy
    Duration: 13 Jun 201914 Jun 2019

    Publication series

    NameProceedings - 2019 8th International Workshop on Advances in Sensors and Interfaces, IWASI 2019

    Conference

    Conference8th International Workshop on Advances in Sensors and Interfaces, IWASI 2019
    CountryItaly
    CityOtranto
    Period13/06/1914/06/19

    Keywords

    • biosensor
    • electrolyte-gated thin film transistor
    • gate functionalization
    • graphene
    • label-free

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