Activities per year
Project Details
Description
The ÅAU Center of Excellence project BACE aims to developing a platform for bioelectronic activation that enables control of cell signals, and, thereby, stimulation of cell functions.
The research is based on the knowledge that the function of the cell – the cell’s behavior – can be changed due to external stimuli that effects the cell-signaling machinery. An important part of the inter-cellular communication is the interaction between ligands (transmitters) and receptors (receivers) on the surface of the cell.
The planned activation platform is a further development of a unique bio-FET-based sensor that was previously produced by our researchers. The sensor enables the possibility to measure the strength of the ligand-receptor interactions with a hitherto unsurpassed sensitivity. At this stage, the results form the basis for new technology.
The research is based on the knowledge that the function of the cell – the cell’s behavior – can be changed due to external stimuli that effects the cell-signaling machinery. An important part of the inter-cellular communication is the interaction between ligands (transmitters) and receptors (receivers) on the surface of the cell.
The planned activation platform is a further development of a unique bio-FET-based sensor that was previously produced by our researchers. The sensor enables the possibility to measure the strength of the ligand-receptor interactions with a hitherto unsurpassed sensitivity. At this stage, the results form the basis for new technology.
| Acronym | BACE |
|---|---|
| Status | Active |
| Effective start/end date | 01/03/19 → 31/12/23 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Activities
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Functional Materials at Biological Interfaces
Ronald Österbacka (Speaker)
14 Mar 2023Activity: Talk or presentation › Public or invited talk
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Organic bioelectronics using water-gated OFETs
Ronald Österbacka (Speaker)
3 Feb 2023Activity: Talk or presentation › Public or invited talk
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Control of cell functions using functional materials and bioelectronics
Ronald Österbacka (Speaker)
19 Jul 2022Activity: Talk or presentation › Public or invited talk
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Organ‐on‐a‐chip technologies for biomedical research and drug development: A focus on the vasculature
Soto veliz, D., Lin, K-L. & Sahlgren, C., 1 Feb 2023, In: Smart Medicine. 2, 1Research output: Contribution to journal › Review Article or Literature Review › peer-review
Open AccessFile215 Downloads (Pure) -
Single Molecule with a Large Transistor – SiMoT cytokine IL-6 Detection Benchmarked against a Chemiluminescent Ultrasensitive Immunoassay Array
Scandurra, C., Björkström, K., Sarcina, L., Imbriano, A., Di Franco, C., Österbacka, R., Bolella, P., Scamarcio, G., Torsi, L. & Macchia, E., 2023, In: Advanced Materials Technologies.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile -
A large-area organic transistor with 3D-printed sensing gate for noninvasive single-molecule detection of pancreatic mucinous cyst markers
Sarcina, L., Viola, F., Modena, F., Picca, R. A., Bollella, P., Di Franco, C., Cioffi, N., Caironi, M., Österbacka, R., Esposito, I., Scamarcio, G., Torsi, L., Torricelli, F. & Macchia, E., Jul 2022, In: Analytical and Bioanalytical Chemistry. 414, 18, p. 5657-5669 13 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)7 Downloads (Pure)
Projects
- 3 Finished
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Forcing the Impossible - Avtryck i det Okända
Hellsten, L., Långbacka, U., Törnroos-Remes, A., Österbacka, R., Slotte, P., Lindfelt, M., Huynh, T. P., Jacquemet, G., Weckman, J., Berger, F., Silagadze, N., Raar, M., Andersson, J., Runeberg, R., Ringbom, A., Da Costa Custodio, L. & Sahlgren, C.
01/01/20 → 31/08/22
Project: Foundation
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SIMBIT: Single molecule bio-electronic smart system array for clinical testing
Österbacka, R., Björkström, K., Tewari, A. & Macchia, E.
01/01/19 → 31/12/22
Project: EU
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SPACE: Spatiotemporal Control of Cell Functions
Österbacka, R., Sahlgren, C., Torsi, L. & Ghafarihashjin, A.
01/09/18 → 31/08/22
Project: Academy of Finland/Other Research Councils