Research output per year
Research output per year
Project Details
Description
The ÅAU Center of Excellence project BACE aims to developing a platform for bioelectronic activation that enables control of cell signals, and, thereby, stimulation of cell functions.
The research is based on the knowledge that the function of the cell – the cell’s behavior – can be changed due to external stimuli that effects the cell-signaling machinery. An important part of the inter-cellular communication is the interaction between ligands (transmitters) and receptors (receivers) on the surface of the cell.
The planned activation platform is a further development of a unique bio-FET-based sensor that was previously produced by our researchers. The sensor enables the possibility to measure the strength of the ligand-receptor interactions with a hitherto unsurpassed sensitivity. At this stage, the results form the basis for new technology.
The research is based on the knowledge that the function of the cell – the cell’s behavior – can be changed due to external stimuli that effects the cell-signaling machinery. An important part of the inter-cellular communication is the interaction between ligands (transmitters) and receptors (receivers) on the surface of the cell.
The planned activation platform is a further development of a unique bio-FET-based sensor that was previously produced by our researchers. The sensor enables the possibility to measure the strength of the ligand-receptor interactions with a hitherto unsurpassed sensitivity. At this stage, the results form the basis for new technology.
| Acronym | BACE |
|---|---|
| Status | Finished |
| Effective start/end date | 01/03/19 → 31/12/23 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Research output
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Reversible stress-induced doping and charge trap generation in IDT-BT EGOFETs
Luukkonen, A., Jern, J., He, Q., Heeney, M. & Osterbacka, R., 2 Jan 2025, In: Journal of Materials Chemistry C. 13, 8, p. 3815-3824 10 p.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile1 Downloads (Pure) -
Analysis of Clinical Samples of Pancreatic Cyst's Lesions with A Multi-Analyte Bioelectronic Simot Array Benchmarked Against Ultrasensitive Chemiluminescent Immunoassay
Scandurra, C., Björkström, K., Caputo, M., Sarcina, L., Genco, E., Modena, F., Viola, F. A., Brunetti, C., Kovács-Vajna, Z. M., Franco, C. D., Haeberle, L., Larizza, P., Mancini, M. T., Österbacka, R., Reeves, W., Scamarcio, G., Wheeler, M., Caironi, M., Cantatore, E. & Torricelli, F. & 3 others, , 17 Jul 2024, In: Advanced Science. 11, 27, 2308141.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)63 Downloads (Pure) -
Label-free electronic detection of peptide post-translational modification with functional enzyme-driven assay at the physical limit
Macchia, E., Björkström, K., Tewari, A., Eskonen, V., Luukkonen, A., Ghafari, A. M., Sarcina, L., Caputo, M., Tong-Ochoa, N., Kopra, K., Pettersson, F., Gounani, Z., Torsi, L., Härmä, H. & Österbacka, R., 21 Aug 2024, In: Cell Reports Physical Science. 5, 8, 101874.Research output: Contribution to journal › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)13 Downloads (Pure)
Activities
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SPIE Optics and Photonics
Österbacka, R. (Participant)
18 Aug 2024 → 24 Aug 2024Activity: Participating in or organising an event › Participating in a conference, workshop, ...
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International Conference on the Science and Technology of Synthetic Metals
Österbacka, R. (Participant)
24 Jun 2024Activity: Participating in or organising an event › Participating in a conference, workshop, ...
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International Winterschool on Bio Electronics
Österbacka, R. (Participant)
10 Mar 2024 → 16 Mar 2024Activity: Participating in or organising an event › Participating in a conference, workshop, ...
Projects
- 3 Finished
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Forcing the Impossible - Avtryck i det Okända
Hellsten, L. (Principal Investigator), Långbacka, U. (Co-Investigator), Törnroos-Remes, A. (Co-Investigator), Österbacka, R. (Co-Investigator), Slotte Russo, P. (Co-Investigator), Lindfelt, M. (Co-Principal Investigator), Huynh, T. P. (Co-Investigator), Jacquemet, G. (Co-Investigator), Weckman, J.-K. (Co-Investigator), Berger, F. (Co-Investigator), Silagadze, N. (Co-Investigator), Raar, M. (Co-Investigator), Andersson, J.-E. (Co-Investigator), Runeberg, R. (Co-Investigator), Ringbom, A. (Co-Investigator), Da Costa Custodio, L. (Co-Investigator) & Sahlgren, C. (Co-Investigator)
01/01/20 → 31/08/22
Project: Foundation
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SIMBIT: Single molecule bio-electronic smart system array for clinical testing
Österbacka, R. (Principal Investigator), Björkström, K. (Co-Investigator), Tewari, A. (Co-Investigator) & Macchia, E. (Co-Investigator)
01/01/19 → 31/12/22
Project: EU
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SPACE: Spatiotemporal Control of Cell Functions
Österbacka, R. (Principal Investigator), Sahlgren, C. (Co-Principal Investigator), Torsi, L. (Co-Principal Investigator) & Ghafarihashjin, A. (Co-Investigator)
01/09/18 → 31/08/22
Project: Research Council of Finland/Other Research Councils