AKT-mediated post-translational regulation of NOTCH3 – decoding the Notch phosphorylation switchboard for targeted therapies in cancer

Sahlgren, Cecilia (Principal Investigator)

Status	Finished
Effective start/end date	01/09/19 → 30/09/22

6 Article
1 Review Article or Literature Review

Investigating Spectral Biomarker Candidates for Migratory Potential in Cancer Cells Using Micro-FTIR and O-PTIR Spectroscopy
Holub, E., Hondl, N., Lin, K.-L., Parikainen, M., Sahlgren, C., Lendl, B. & Ramer, G., 18 Feb 2026, In: ACS Measurement Science Au. 6, 1, p. 96-106
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
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4 Citations (Scopus)

64 Downloads (Pure)
Jagged1 regulates extracellular matrix deposition and remodeling in triple-negative breast cancer
Parikainen, M., Suwal, U., Rappu, P., Heino, J. & Sahlgren, C., 18 Mar 2026, In: Science Advances. 12, 12
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
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4 Citations (Scopus)

31 Downloads (Pure)
GIT1 protects against breast cancer growth through negative regulation of Notch
Zhang, S., Miyakawa, A., Wickström, M., Dyberg, C., Louhivuori, L., Varas-godoy, M., Kemppainen, K., Kanatani, S., Kaczynska, D., Ellström, I. D., Elfman, L., Kronqvist, P., Repo, H., Mikoshiba, K., Sahlgren, C., Johnsen, J. I. & Uhlén, P., 22 Mar 2022, In: Nature Communications. 13, 1, 1537.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
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14 Citations (Scopus)

68 Downloads (Pure)

The Notch ligand Jagged1 regulates extracellular matrix production and organization in triple-negative breast cancer
Parikainen, M. (Creator), Suwal, U. (Creator), Rappu, P. (Creator), Jyrki, H. (Creator) & Sahlgren, C. (Creator), NCBI, 9 Feb 2026
DOI: GSE296927, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296927
Dataset

OptoNotch: Using light to activate Notch signaling
Kałafut, J., Czapiński, J., Przybyszewska-Podstawka, A., Czerwonka, A., Odrzywolski, A., Sahlgren, C. & Rivero Müller, A.
20/05/22
1 Media contribution
Press/Media: Social Media Activity/Appearance
New Research Data on the Regulation of Hormone-dependent Breast Cancer
Sahlgren, C., Koskinen, P. J., Santio, N. M. & Landor, S.
22/04/21
1 Media contribution
Press/Media
Nya forskningsrön om regleringen av hormonell bröstcancer
Sahlgren, C., Landor, S., Santio, N. M. & Koskinen, P. J.
22/04/21
1 Media contribution
Press/Media