A colon-specific mouse model for colorectal cancer: Keratins as tumor suppressors and guardians of intestinal health

Toivola, Diana (Principal Investigator)

Status	Active
Effective start/end date	01/09/20 → 31/08/24

Funding

Research Council of Finland: €513,249.00

3 Article
1 Review Article or Literature Review

Colonocyte keratin 7 is expressed de novo in inflammatory bowel diseases and associated with pathological changes and drug-resistance
Polari, L., Tenhami, M., Anttila, S., Helenius, T., Kujari, H., Kallajoki, M., Voutilainen, M. & Toivola, D. M., 23 Dec 2022, In: Scientific Reports. 12, 1, 10 p., 22213.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
3 Citations (Scopus)

9 Downloads (Pure)
Keratiinit suoliston epiteelisoluissa ja paksusuolensyövän analytiikassa
Polari, L., Voutilainen, M., Kallajoki, M. & Toivola, D., Jan 2022, In: Duodecim: lääketieteellinen aikakauskirja. 138, 10, p. 889 896 p., 138.
Research output: Contribution to journal › Review Article or Literature Review › peer-review

Open Access
File

2 Downloads (Pure)
Targeted deletion of keratin 8 in intestinal epithelial cells disrupts tissue integrity and predisposes to tumorigenesis in the colon
Stenvall, C-G. A., Tayyab, M., Grönroos, T. J., Ilomäki, M. A., Viiri, K., Ridge, K. M., Polari, L. & Toivola, D. M., Jan 2022, In: Cellular and Molecular Life Sciences. 79, 1, 17 p., 10.
Research output: Contribution to journal › Article › Scientific › peer-review

Open Access
File
11 Citations (Scopus)

26 Downloads (Pure)