JNK-regulated phosphoproteome links synaptic and metabolic pathways to mood regulation

Ye Hong (Creator)
Valentina Siino (Creator)
Dani Flinkman (Creator)
Prasannakumar Deshpande (Creator)
Sylvia Ortega Martinez (Creator)
Veronica Fagerholm (Creator)
Artemis Varidaki (Creator)
Pierre Heemeryck (Creator)
Christel Sourander (Creator)
Peter James (Creator)
Eleanor Coffey (Creator)

Dataset

Description

JNKs play critical roles in neuronal damage associated with neurodegenerative disease and inhibitors of JNK1 have shown anxiolytic and anti-depressive effects in mice. In this study, we analyze the phosphoproteomes of hippocampus and nucleus accumbens in mice treated with DJNKI-1, a JNK inhibitor.

Date made available	1 Dec 2025
Publisher	PRIDE - Proteomics Identification Database EMBL-EBI

Access Dataset

https://www.ebi.ac.uk/pride/archive/projects/PXD060057

Cite this

DataSetCite

Hong, Y. (Creator), Siino, V. (Creator), Flinkman, D. (Creator), Deshpande, P. (Creator), Ortega Martinez, S. (Creator), Fagerholm, V. (Creator), Varidaki, A. (Creator), Heemeryck, P. (Creator), Sourander, C. (Creator), James, P. (Creator), Coffey, E. (Creator) (1 Dec 2025). JNK-regulated phosphoproteome links synaptic and metabolic pathways to mood regulation. PRIDE - Proteomics Identification Database EMBL-EBI.