Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"

  • Tommaso Ristori (Creator)
  • Oscar Stassen (Creator)
  • Cecilia Sahlgren (Creator)
  • Sandra Loerakker (Creator)
  • Sandra Loerakker (Creator)



This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.
Date made available20 Oct 2020

Cite this