Serotonin in Trichinella pseudospiralis: An immunocytochemical study

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: N.B. TERENINA, N. B. MOCHALOVA, I.M. ODOEVSKAYA, N.D. KRESHCHENKO, M.K.S. GUSTAFSSON, H-P. FAGERHOLM
Publisher: De Gruyter
Publication year: 2016
Journal: Helminthologia
Volume number: 53
Issue number: 2
Start page: 113
End page: 119
eISSN: 1336-9083


Abstract

This is the first report on the presence and localization of the neurotransmitter serotonin (5-HT) in the nervous system of the nematode Trichinella pseudospiralis, the causative agent of trichinellosis. The orientation of the 5-HT-immunoreactive (5-HT-IR) nerve cells in the adult worm is described. In the anterior region of the worm 5-HT-IR occurs in 7 neurons. Longitudinal nerve cords extend posteriorly from the anterior end. They are connected by transverse commissures. The vulval area is intensively supplied with 5-HT-IR nerve cells and fibres forming a plexus. Two rows of small 5HT-IR structures, hypodermal glands, are visible along the whole nematode body. Because of the conserved structural features among nematodes the 5-HT-IR neurons observed are likely to have counterparts in the model worm, Caenorhabditis elegans. Some basic differences are evident and demand further study

Last updated on 2019-16-07 at 05:32