Lignans 7-hydroxymatairesinol and 7-hydroxymatairesinol 2 exhibit anti-inflammatory activity in human aortic endothelial cells

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Eliana Spilioti, Bjarne Holmbom, Athanasios G. Papavassiliou, Paraskevi Moutsatsou
Publication year: 2014
Journal: Molecular Nutrition and Food Research
Volume number: 58
Issue number: 4
Start page: 749
End page: 759
eISSN: 1613-4133


Our results demonstrated that the lignans HMR and HMR2, dominant in cereals, such as in wheat, triticale, oat, barley, millet, corn bran, and in amaranth whole grain, exhibit stron anti-infammatory properties in endothelial cells, at least in part, through attenuation of nuclear factor-кB and extracellular regulated kinase phosphorylation.


7-Hydoxymatairesinol, Adhesion molecules, Atherosclerosis, Endothelial cells, Lignans

Last updated on 2020-14-08 at 05:21