High-definition tDCS of the temporo-parietal cortex enhances access to newly learned words

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)

Interna författare/redaktörer

Publikationens författare: Garon Perceval, Andrew K. Martin, David A. Copland, Matti Laine, Marcus Meinzer
Förläggare: Nature Publishing Group
Publiceringsår: 2017
Tidskrift: Scientific Reports
Volym: 7


Learning associations between words and their referents is crucial for language learning in the
developing and adult brain and for language re-learning after neurological injury. Non-invasive
transcranial direct current stimulation (tDCS) to the posterior temporo-parietal cortex has been
suggested to enhance this process. However, previous studies employed standard tDCS set-ups
that induce diffuse current flow in the brain, preventing the attribution of stimulation effects to the
target region. This study employed high-definition tDCS (HD-tDCS) that allowed the current flow to
be constrained to the temporo-parietal cortex, to clarify its role in novel word learning. In a shamcontrolled,
double-blind, between-subjects design, 50 healthy adults learned associations between
legal non-words and unfamiliar object pictures. Participants were stratified by baseline learning ability
on a short version of the learning paradigm and pairwise randomized to active (20 mins; N = 25) or sham
(40 seconds; N = 25) HD-tDCS. Accuracy was comparable during the baseline and experimental phases
in both HD-tDCS conditions. However, active HD-tDCS resulted in faster retrieval of correct word-picture
pairs. Our findings corroborate the critical role of the temporo-parietal cortex in novel word
learning, which has implications for current theories of language acquisition.

Senast uppdaterad 2020-29-01 vid 03:20