Therapeutic Potential of Polymer-Coated Mesoporous Silica Nanoparticles

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Bansal KK, Mishra DK, Rosling A, Rosenholm JM
Förläggare: Multidisciplinary Digital Publishing Institute
Publiceringsår: 2020
Tidskrift: Applied Sciences
Volym: 10
Nummer: 1


Abstrakt

Mesoporous silica nanoparticles (MSNs) find tremendous applications in
drug delivery due to several advantages such as their easy fabrication
process, high drug loading, biodegradability, biocompatibility, and so
forth. Nevertheless, despite several advantages, the use of this
striking drug delivery carrier is restricted due to premature drug
release owing to the porous structure. Coating of the pores using
polymers has emerged as a great solution to this problem. Polymer
coatings, which act as gatekeepers, avoid the premature release of
loaded content from MSNs and offers the opportunity for controlled and
targeted drug delivery. Therefore, in this review, we have compiled the
polymer-based coating approaches used in recent years for improving the
drug delivery capability of MSNs. This manuscript provides an insight
into the research about the potential of polymer-coated MSNs, allowing
the selection of right polymer for coating purposes according to the
desired application.


Nyckelord

controlled drug delivery, Customized drug delivery device, drug delivery, drug-delivery systems, Drug delivery systems, mesoporous materials, Mesoporous silica, Micro-Mesoporous material, polymer


Dokument


Senast uppdaterad 2020-07-04 vid 06:44