Nanogels as drug-delivery systems: a comprehensive overview

A2 Granskningsartikel, litteraturgranskning, systematisk granskning


Interna författare/redaktörer


Publikationens författare: Suhail M, Rosenholm JM, Minhas MU, Badshah SF, Naeem A, Khan KU, Fahad M
Förläggare: Future Science Ltd.
Publiceringsår: 2019
Tidskrift: Therapeutic Delivery
Volym: 10
Nummer: 11
ISSN: 2041-5990


Abstrakt

Nanogels have attracted considerable attention as nanoscopic drug
carriers, particularly for site-specific or time-controlled delivery of
bioactive mediators. A high diversity of polymer systems and the simple
modification of their physicochemical features have provided
multipurpose forms of nanogel preparations. Nanogels have outstandingly
high stability, drug loading ability, biologic consistence, good
permeation capability and can be responsive to environmental stimuli.
Great potential has been shown by nanogels in many fields including
delivery of genes, chemotherapy drugs, diagnosis, targeting of specific
organs and several others. This review focuses mainly on different types
of nanogels, methods of preparation including methods of drug loading,
different modes of biodegradation mechanisms as well as main mechanisms
of drug release from nanogels. Recent applications of nanogels are also
briefly discussed and exemplified.


Senast uppdaterad 2020-02-04 vid 04:31