Nanodiamond based complexes for prolonged dexamethasone release

A4 Conference proceedings


Internal Authors/Editors


Publication Details

List of Authors: Laptinskiy KA, Kettiger H, Shenderova OA, Burikov SA, Rosenholm JM, Dolenko TA
Editors: Dmitry Engelevich Postnov
Publisher: International Society for Optics and Photonics
Publication year: 2019
Journal: Proceedings of SPIE
Publisher: Society of Photo-Optical Instrumentation Engineers (SPIE)
Book title: Saratov Fall Meeting 2018: Computations and Data Analysis: from Nanoscale Tools to Brain Functions
Title of series: Proceedings of SPIE
Volume number: 11067
ISBN: 9781510628243


Abstract

In the article for the first time the properties of nanodiamond
complexes with dexamethasone obtained by two different approaches -
attachment of the drug to the surface of nanodiamond and to the
nanodiamond, covered by silica layer – were compared. It was found that
the synthesized nanocomposite ND@silica@Dex is able to retain a greater
amount of drug and allows achieving prolonged release of dexamethasone.
These properties of the complexes ND@silica@Dex provide prospects for
their use as drug carries.


Keywords

nanodiamonds

Last updated on 2020-28-02 at 06:05