BODIL: a molecular modeling environment for structure-function analysis and drug design.

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Lehtonen, Still, Rantanen, Ekholm, Björklund, Iftikhar, Huhtala, Repo, Jussila, Jaakkola, Pentikäinen, Nyrönen, Salminen, Gyllenberg, Johnson
Publiceringsår: 2004
Tidskrift: Journal of Computer-Aided Molecular Design
Tidskriftsakronym: J Comput Aided Mol Des
Volym: 18
Nummer: 6
Artikelns första sida, sidnummer: 401
Artikelns sista sida, sidnummer: 19
ISSN: 0920-654X


Abstrakt

BODIL is a molecular modeling environment geared to help the user to quickly identify key features of proteins critical to molecular recognition, especially (1) in drug discovery applications, and (2) to understand the structural basis for function. The program incorporates state-of-the-art graphics, sequence and structural alignment methods, among other capabilities needed in modern structure-function-drug target research. BODIL has a flexible design that allows on-the-fly incorporation of new modules, has intelligent memory management, and fast multi-view graphics. A beta version of BODIL and an accompanying tutorial are available at http://www.abo.fi/fak/mnf/bkf/research/johnson/bodil.html.

Senast uppdaterad 2020-04-04 vid 09:22