Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Mishra V, Bansal KK, Verma A, Yadav N, Thakur S, Sudhakar K, Rosenholm JM
Publisher: MDPI
Publication year: 2018
Journal: Pharmaceutics
Volume number: 10
Issue number: 4
ISSN: 1999-4923


Abstract

Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.


Keywords

Colloidal nanoparticles, cytotoxicity, Drug delivery, drug-delivery systems, Nanoparticles, solid lipid


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Last updated on 2019-12-12 at 02:47