Solid Lipid Nanoparticles: Emerging Colloidal Nano Drug Delivery Systems

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Mishra V, Bansal KK, Verma A, Yadav N, Thakur S, Sudhakar K, Rosenholm JM
Förläggare: MDPI
Publiceringsår: 2018
Tidskrift: Pharmaceutics
Volym: 10
Nummer: 4
ISSN: 1999-4923


Abstrakt

Solid lipid nanoparticles (SLNs) are nanocarriers developed as substitute colloidal drug delivery systems parallel to liposomes, lipid emulsions, polymeric nanoparticles, and so forth. Owing to their unique size dependent properties and ability to incorporate drugs, SLNs present an opportunity to build up new therapeutic prototypes for drug delivery and targeting. SLNs hold great potential for attaining the goal of targeted and controlled drug delivery, which currently draws the interest of researchers worldwide. The present review sheds light on different aspects of SLNs including fabrication and characterization techniques, formulation variables, routes of administration, surface modifications, toxicity, and biomedical applications.


Nyckelord

Colloidal nanoparticles, cytotoxicity, Drug delivery, drug-delivery systems, Nanoparticles, solid lipid


Dokument


Senast uppdaterad 2019-10-12 vid 02:54