A method for optical imaging and monitoring of the excretion of fluorescent nanocomposites from the body using artificial neural networks

A1 Journal article (refereed)

Internal Authors/Editors

Publication Details

List of Authors: Sarmanova OE, Burikov SA, Dolenko SA, Isaev IV, Laptinskiy KA, Prabhakar N, Karaman DŞ, Rosenholm JM, Shenderova OA, Dolenko TA
Publisher: Elsevier
Publication year: 2018
Journal: Nanomedicine: Nanotechnology, Biology and Medicine
Volume number: 14
Issue number: 4
Start page: 1371
End page: 1380
ISSN: 1549-9634


In this study, a new approach to the implementation of optical imaging of fluorescent nanoparticles in a biological medium using artificial neural networks is proposed. The studies were carried out using new synthesized nanocompositesnanometer graphene oxides, covered by the poly(ethylene imine)-poly(ethylene glycol) copolymer
and by the folic acid. We present an example of a successful solution
of the problem of monitoring the removal of nanocomposites based on nGO
and their components with urine using fluorescent spectroscopy
and artificial neural networks. However, the proposed method is
applicable for optical imaging of any fluorescent nanoparticles used as
theranostic agents in biological tissue.


Artificial neural networks, bioimaging, fluorescent imaging probes

Last updated on 2019-20-04 at 04:54