The antimicrobial effects of wood-associated polyphenols on food pathogens and spoilage organisms.

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Carme Plumed-Ferrer, Kati Väkeväinen, Heli Komulainen, Maarit Rautiainen, Annika Smeds, Jan-Erik Raitanen, Patrik Eklund, Stefan Willför, Hanna-Leena Alakomi, Maaria Saarela, Atte von Wright
Publisher: Elsevier
Publication year: 2013
Journal: International Journal of Food Microbiology
Journal acronym: Int J Food Microbiol
Volume number: 164
Issue number: 1
Start page: 99
End page: 107
ISSN: 1879-3460
eISSN: 1879-3460


Abstract

The antimicrobial effects of the wood-associated polyphenolic compounds pinosylvin, pinosylvin monomethyl ether, astringin, piceatannol, isorhapontin, isorhapontigenin, cycloXMe, dHIMP, ArX, and ArXOH were assessed against both Gram-negative (Salmonella) and Gram-positive bacteria (Listeria monocytogenes, Staphylococcus epidermidis, Staphylococcus aureus) and yeasts (Candida tropicalis, Saccharomyces cerevisiae). Particularly the stilbenes pinosylvin, its monomethyl ether and piceatannol demonstrated a clear antimicrobial activity, which in the case of pinosylvin was present also in food matrices like sauerkraut, gravlax and berry jam, but not in milk. The destabilization of the outer membrane of Gram-negative microorganisms, as well as interactions with the cell membrane, as indicated by the NPN uptake and LIVE/DEAD viability staining experiments, can be one of the specific mechanisms behind the antibacterial action. L. monocytogenes was particularly sensitive to pinosylvin, and this effect was also seen in L. monocytogenes internalized in intestinal Caco2 cells at non-cytotoxic pinosylvin concentrations. In general, the antimicrobial effects of pinosylvin were even more prominent than those of a related stilbene, resveratrol, well known for its various bioactivities. According to our results, pinosylvin could have potential as a natural disinfectant or biocide in some targeted applications.


Keywords

Food spoilage, Listeria monocytogenes, Pinosylvin, Salmonella, Stilbenes, Wood associated phenolic compounds

Last updated on 2019-15-12 at 03:04