Intermediate filament dynamics

A2 Review article, Literature review, Systematic review


Internal Authors/Editors


Publication Details

List of Authors: Eriksson JE, Opal P, Goldman RD
Publication year: 1992
Journal: Current Opinion in Cell Biology
Journal acronym: Curr Opin Cell Biol
Volume number: 4
Issue number: 1
Start page: 99
End page: 104
ISSN: 0955-0674


Abstract

The view of intermediate filaments as static cytoskeletal elements is changing. Studies of exogenous intermediate filament proteins, either microinjected or expressed from transfected genes, have demonstrated that a continuous incorporation of subunits into the polymerized filaments is taking place. This incorporation appears to be required for maintaining normal cytoplasmic networks of intermediate filaments. At the post-translational level, phosphorylation is an important factor in regulating dynamic aspects of intermediate filament organization and structure.

Last updated on 2019-07-12 at 03:05