Polyethylenimine-modified metal oxides for fabrication of packed capillary columns for capillary electrochromatography and capillary liquid chromatography

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Susanne K. Wiedmer, Giovanni D'Orazio, Jan-Henrik Smått, Delphine Bourdin, Clara Baños-Pérez, Motolani Sakeye, Maarit Kivilompolo, Matias Kopperi, José Ruiz-Jiménez, Salvatore Fanali, Marja-Liisa Riekkola
Publiceringsår: 2011
Tidskrift: Journal of Chromatography A
Tidskriftsakronym: J Chromatogr A
Volym: 1218
Nummer: 30
Artikelns första sida, sidnummer: 5020
Artikelns sista sida, sidnummer: 9
ISSN: 1873-3778


Abstrakt

The need for novel packing materials in both capillary electrochromatography (CEC) and capillary liquid chromatography (CLC) is apparent and the development towards more selective, application-oriented chromatographic phases is under progress world-wide. In this study we have synthesized new polyethyleneimine (PEI) functionalized Mn(2)O(3), SiO(2), SnO(2), and ZrO(2) particles for the fabrication of packed capillary columns for CEC and CLC. The nanocasting approach was successful for the preparation of functionalized metal oxide materials with a controlled porosity and morphology. PEI functionalization was done using ethyleneimine monomers to create particles which are positively charged in aqueous solution below pH 9. This functionalization allowed the possibility to have both hydrophobic (due to its alkyl chain) and ionic interactions (due to positively charged amino groups) with selected compounds. For comparison aminopropyl-functionalized silica was also synthesized and tested. Both slurry pressure and electrokinetic packing procedures used gave similar results, but fast sedimentation of the material caused some problems during the packing. The high stability and wide pH range of PEI-functionalized SiO(2) material, with potential for hydrophobic and electrostatic interactions, proved to be useful for the CEC and CLC separation of some model acidic and neutral compounds.

Senast uppdaterad 2020-26-02 vid 07:25