Effects of normal aging on event-related desynchronization/synchronization during a memory task in humans

A1 Journal article (refereed)


Internal Authors/Editors


Publication Details

List of Authors: Karrasch M, Laine M, Rapinoja P, Krause CM
Publisher: ELSEVIER SCI IRELAND LTD
Publication year: 2004
Journal: Neuroscience Letters
Journal acronym: NEUROSCI LETT
Volume number: 366
Issue number: 1
Start page: 18
End page: 23
Number of pages: 6
ISSN: 0304-3940


Abstract

Event-related desynchronization (ERD) and event-related synchronization (ERS) of the 1-20Hz EEG frequencies were studied using wavelet transforms in young (n = 10, mean age 22) and elderly subjects (n = 10, mean age 65) performing an auditory Sternberg memory task with words as stimuli. In both age groups, encoding of the four-word memory set elicited ERS in the theta and alpha frequency range. Theta ERS, and ERD in the alpha and beta bands were observed during retrieval. During encoding, the elderly showed greater alpha ERS and smaller theta ERS. During retrieval, smaller alpha ERD and theta ERS was found in the elderly subjects. Also, in the elderly, beta ERD was elicited in the late time window during retrieval. The statistically significant differences between the age groups were more marked during retrieval than during encoding. The results indicate that although the two groups performed equally well behaviorally in the task and the elderly subjects were cognitively intact, normal aging affects oscillatory theta, alpha and beta responses particularly during retrieval from working memory. The ERD/ERS patterns of the elderly resemble those of children found in a recent study, which might suggest that those memory-related brain processes that evolve later in childhood are the first to be affected in older age. (C) 2004 Elsevier Ireland Ltd. All rights reserved.


Keywords

aging, EEG, ERD, ERS, event-related desynchronization, event-related synchronization, working memory

Last updated on 2019-16-10 at 02:50