In vitro behavior of yttrium silica sol-gel microspheres

A1 Originalartikel i en vetenskaplig tidskrift (referentgranskad)


Interna författare/redaktörer


Publikationens författare: Cacaina D, Viitala R, Jokinen M, Ylanen H, Hupa M, Simon S
Publiceringsår: 2005
Tidskrift: Key Engineering Materials
Tidskriftsakronym: KEY ENG MAT
Volym: 284-286
Artikelns första sida, sidnummer: 411
Artikelns sista sida, sidnummer: 414
Antal sidor: 4
ISSN: 1013-9826


Abstrakt

Biodegradable silica microspheres containing neutron activable yttrium cations were investigated as a potential material for in situ radiotherapy of cancers. The sol-gel method used for preparing the microspheres allows obtaining at relative low temperatures materials of high purity and homogeneity, with controlled rate of biodegradability. The influence of yttrium on the biodegradability of the silica microspheres was studied in a simulated body fluid (SBF). The chemical durability of the microspheres was investigated under in vitro conditions and the concentration of yttrium released from the microspheres was determined.


Nyckelord

bioactive glasses, release behaviour, SBF, sol gel, yttrium

Senast uppdaterad 2020-26-02 vid 05:47